Novel avian-origin influenza A (H7N9) virus attachment to the respiratory tract of five animal models.
نویسندگان
چکیده
We determined the pattern of attachment of the avian-origin H7N9 influenza viruses A/Anhui/1/2013 and A/Shanghai/1/2013 to the respiratory tract in ferrets, macaques, mice, pigs, and guinea pigs and compared it to that in humans. The H7N9 attachment pattern in macaques, mice, and to a lesser extent pigs and guinea pigs resembled that in humans more closely than the attachment pattern in ferrets. This information contributes to our knowledge of the different animal models for influenza.
منابع مشابه
Human infection with a novel avian-origin influenza A (H7N9) virus.
BACKGROUND Infection of poultry with influenza A subtype H7 viruses occurs worldwide, but the introduction of this subtype to humans in Asia has not been observed previously. In March 2013, three urban residents of Shanghai or Anhui, China, presented with rapidly progressing lower respiratory tract infections and were found to be infected with a novel reassortant avian-origin influenza A (H7N9)...
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ورودعنوان ژورنال:
- Journal of virology
دوره 88 8 شماره
صفحات -
تاریخ انتشار 2014